Novel Small Molecule FosB/AP-1 Inhibitors for the Prevention of Proliferative Vascular Disorders

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1030769

Funding Status
Closed

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Funded Activity Summary

This project examines the effect of a novel FosB/AP-1 inhibitor (LK001) on neointima formation after injury in animal models of restenosis, atherosclerosis and abdominal aortic aneurysm, and a human ex vivo model of graft stenosis Given the current prevalence of CVD in Australia and the increasing demographic of susceptible individuals in the ageing population, this project has enormous clinical implications.

Funded Activity Details

Start Date: 01-01-2012

End Date: 01-01-2013

Funding Scheme: NHMRC Project Grants

Funding Amount: $343,597.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Cardiology (incl. Cardiovascular Diseases)

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

artery wall | cell growth | injury | proliferation | restenosis | smooth muscle cell

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