Activation Transcription Factor-4: Novel Regulator of Smooth Muscle Cell Repair and Intimal Thickening through Tenascin C

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1030767

Funding Status
Closed

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Funded Activity Summary

CVD represents the most important cause of morbidity and mortality in the world, accounting for 35% of all deaths in Australia. Smooth muscle cell growth accounts for a range of vascular proliferative disorders. This project focuses on understanding the role of ATF-4 as a new key regulator of SMC proliferation and intimal thickening in injured vessels. Moreover, strategies targeting ATF-4 will facilitate future therapeutic strategies to control intimal thickening in patients with vascular disease.

Funded Activity Details

Start Date: 01-01-2012

End Date: 01-01-2013

Funding Scheme: NHMRC Project Grants

Funding Amount: $228,313.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Medical and Health Sciences

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

blood vessels | growth factor | injury | signalling | smooth muscle cell

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