Nuclear retention-and-release of RNA: a naturally-occurring mechanism for controlling gene expression

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1030695

Funding Status
Closed

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Funded Activity Summary

The deliberate retention of messenger RNA in the nucleus is a newly-discovered biological mechanism used by cells to control which genes are made into proteins, and when. This is a fundamental process in health and disease. The project will employ cutting edge molecular and cellular techniques to discover the principles underpinning nuclear retention. These insights will allow the development of new methods to spatially and temporally control gene expression in diverse gene therapy applications.

Funded Activity Details

Start Date: 01-01-2012

End Date: 01-01-2014

Funding Scheme: Project Grants

Funding Amount: $428,753.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Genome Structure and Regulation

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

RNA binding proteins | RNA processing | gene expression | gene regulation | gene therapy | molecular basis of disease | protein complexes | protein localisation

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