Mechanism and treatment of sympathetically maintained pain

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1030379

Funding Status
Closed

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Funded Activity Summary

This project investigates a crucial but neglected element in the mechanism of chronic pain that develops after nerve and tissue injury. In particular, our aim is to establish whether expression of a chemical target of the neurotransmitter noradrenaline increases in the painful skin of affected patients, and whether medication that blocks this target alleviates inflammation and pain. If so, this may open up new avenues for treatment for previously intractable pain syndromes.

Funded Activity Details

Start Date: 01-01-2012

End Date: 01-01-2015

Funding Scheme: Project Grants

Funding Amount: $482,962.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Peripheral Nervous System

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

adrenoceptors | confocal microscopy | diabetic neuropathy | immunohistochemistry | inflammatory cytokines | keratinocytes | neuropathic pain | nociception | pain mechanisms | peripheral nerve injury

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