Profiling global inflammatory signatures for GPCRs in human macrophages

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1030169

Funding Status
Closed

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Funded Activity Summary

Macrophages are important white blood cells of the immune system. They trigger inflammatory responses to infection or injury, but prolonged inflammatory responses can lead to chronic diseases. In this project we aim to better understand how macrophages sense the outside environment, how external signals trigger inflammatory processes, how this leads to diseases such as autoimmune and inflammatory diseases, cancer and cardiovascular diseases, and how to control them with drugs.

Funded Activity Details

Start Date: 01-01-2012

End Date: 01-01-2014

Funding Scheme: Project Grants

Funding Amount: $687,770.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Signal Transduction

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

G protein-coupled receptors | Toll-like receptors | cytokines | drug discovery | gene expression | inflammatory mediators | innate immunity | macrophage activation | microarrays | signalling pathways

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