Nodal signalling in male germ cell development: Balancing fertility and testicular cancer susceptibility

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1030146

Funding Status
Closed

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Funded Activity Summary

Testicular cancer is the most common type of cancer in men aged 20-40 years, and its incidence has doubled in the last 30 years. It is sometimes fetal and often results in infertility. We have discovered new genes that regulate testicular cell behaviour in the developing fetus, and here test the concept that defects in these genes might disrupt cell behaviour to the point where cancers form during adult life. Outcomes may lead to new ways to diagnose and treat testicular cancers.

Funded Activity Details

Start Date: 01-01-2012

End Date: 01-01-2014

Funding Scheme: Project Grants

Funding Amount: $536,595.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Developmental Genetics (incl. Sex Determination)

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

embryonic development | germ cells | mouse models | sexual differentiation | signalling pathways | spermatogenesis | testis development

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