Control of bone remodelling by osteoclastic metabolism of vitamin D

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1029926

Funding Status
Closed

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Funded Activity Summary

Vitamin D is essential for bone health. This study will build on our extensive body of preliminary data to investigate the extent to which bone-resorbing osteoclasts are controlled by circulating levels of the pro-hormone 25-hydroxyvitamin D. Our work will identify new approaches to the treatment of osteoporosis, by targetting the osteoclast as a vitamin D-responsive cell type.

Funded Activity Details

Start Date: 01-01-2012

End Date: 01-01-2014

Funding Scheme: Project Grants

Funding Amount: $694,635.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Medical Biochemistry and Metabolomics not elsewhere classified

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

autocrine/paracrine regulation | bone remodelling | bone resorption | cytochrome P450 | metabolism | osteoclast biology | osteoporosis | vitamin D

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