Modelling epigenomic change during early breast carcinogenesis using in vitro and in vivo model systems

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1029579

Funding Status
Closed

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Funded Activity Summary

Epigenetics describes how genes can be turned on and off without a change in the DNA sequence. Epigenetic changes are common and often occur early in cancer, but we do not know where or how epigenetic changes occur in cancer. In this proposal we will create the first detailed map of the epigenetic landscape of normal and cancer breast cells. These maps will allow us to predict where epigenetic lesions occur in breast cancer, which will have important diagnostic and therapeutic value for cancer treatments.

Funded Activity Details

Start Date: 01-01-2012

End Date: 01-01-2015

Funding Scheme: Project Grants

Funding Amount: $743,360.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Cancer Diagnosis

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

DNA methylation | cancer biology | cancer detection | chromatin structure | epigenetics

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