Expression and secretion of large clostridial toxins from the pathogenic clostridia.

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1029556

Funding Status
Closed

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Funded Activity Summary

The large clostridial toxins are an important family of bacterial virulence factors that includes toxins from many disease-causing clostridial species. Despite their impact on public health, pathogenesis of disease caused by these bacteria is poorly understood. We will analyse how these bacteria regulate the production and secretion of the large toxins, which will give us a better understanding of the mechanisms of disease causation as well as identifying novel common therapeutic targets.

Funded Activity Details

Start Date: 01-01-2012

End Date: 01-01-2014

Funding Scheme: Project Grants

Funding Amount: $332,258.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Medical Bacteriology

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

bacterial evolution | bacterial genetics | bacterial infection | bacterial pathogen | bacterial pathogenesis | bacterial toxins | bacterial virulence

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