Targeting early cellular damage during secondary degeneration using nanosphere-based drug delivery

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1028681

Funding Status
Closed

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Funded Activity Summary

After brain injury, there are no treatments to stop the spread of damage to intact tissue, a process involving different cell types and biochemical events. Clinical trials have targeted one event and have failed because large therapeutic doses are toxic and because combined treatments are needed to target different events. We will harness nanotechnology to target delivery of small, sustained doses of one or more drugs to specific cell types and biochemical events to stop the spread of damage.

Funded Activity Details

Start Date: 01-01-2012

End Date: 01-01-2015

Funding Scheme: Project Grants

Funding Amount: $424,407.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Cellular Nervous System

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

astrocytes | calcium homeostasis | drug targeting | nanotechnology | neuronal degeneration | oxidative stress | secondary

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