Small Molecule Modulators of Complement in Metabolism and Obesity

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1028423

Funding Status
Closed

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Funded Activity Summary

We have discovered that certain inflammatory proteins in the blood that are produced in the immune response to infection are involved in regulating the storage and burn off of fat in adipose tissue in the abdomen. These proteins bind to the surfaces of both fat and immune cells. We will study the effects of new drugs that compete with these blood proteins for the surfaces of these cells, since our experiments indicate that such drugs can potentially prevent and reverse fat deposition in rats fed a high-fat, high-carbohydrate, diet.

Funded Activity Details

Start Date: 01-01-2012

End Date: 01-01-2015

Funding Scheme: Project Grants

Funding Amount: $682,820.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Pharmacology and Pharmaceutical Sciences not elsewhere classified

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

anti-inflammatory agents | biochemistry | cardiovascular risk factors | drug design | obesity | pharmacology

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