Role of IRAP in Alzheimer's disease

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1028403

Funding Status
Closed

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Funded Activity Summary

Alzheimer’s disease is a progressive brain disease which is results in memory loss and brain cell death. All currently prescribed drugs treat the memory loss but are unable to stop the deterioration of brain cells. We have previously developed a class of drugs that reverse memory loss targeting – these drugs target a protein called IRAP. We recently found that these drugs also reduce the disease pathology. This research proposal aims to investigate the role of IRAP in the initiation or progression of Alzheimer’s disease pathology.

Funded Activity Details

Start Date: 01-01-2012

End Date: 01-01-2013

Funding Scheme: Project Grants

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Central Nervous System

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

Alzheimer disease | amyloid beta-protein | enzyme inhibitors | memory | memory disorders | neuroinflammation | peptidases | senile plaques | transgenic mouse

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