Characterization of a novel secretion and attachment system necessary for the formation of a virulence coat in Porphyromonas gingivalis

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1027812

Funding Status
Closed

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Funded Activity Summary

In this study we will characterize a novel bacterial secretion system that we have discovered. This system mediates the secretion of proteins from the bacterial cell and their attachment to the cell surface. This system is essential for the virulence of a bacterium associated with severe gum disease. The chacterization of this system may offer opportunities for the development of new treatments to target this disease.

Funded Activity Details

Start Date: 01-01-2012

End Date: 01-01-2014

Funding Scheme: Project Grants

Funding Amount: $828,857.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Medical Microbiology not elsewhere classified

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

Porphyromonas gingivalis | lipopolysaccharide | protease | secretory pathway | virulence factors

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