Retinoic acid receptor-related orphan receptors and the regulation of metabolism:insights into diabetes and obesity

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1027484

Funding Status
Closed

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Funded Activity Summary

Nuclear receptors (NRs) function as hormone dependent DNA binding proteins important in sustaining human health, highlighted by the array of medicines that target these proteins for human well being. ROR alpha is one such protein that we have shown regulates fat mass, obesity, and glucose tolerance. Obesity and diabetes are often linked with inflammation. We will examine how ROR controls inflammation during metabolic disease.

Funded Activity Details

Start Date: 01-01-2012

End Date: 01-01-2014

Funding Scheme: Project Grants

Funding Amount: $760,799.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Signal Transduction

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

adipose tissue | bioinformatics | endocrinology | expression profiling | gene regulation | inflammation | metabolism | nuclear receptors | signal transduction | skeletal muscle

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