Pathogenic role of changes in the extracellular environment of retinal ganglion cells in glaucoma

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1027170

Funding Status
Closed

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Funded Activity Summary

There are an estimated 60 million glaucoma sufferers worldwide. Glaucoma is associated with elevated pressure within the eye but the mechanisms by which this leads to vision loss are not clear. We propose to test a new hypothesis that it is tissue stress that is responsible for the ganglion cell death in glaucoma. We propose to measure key parameters of the cellular environment in an animal model of raised intraocular pressure and determine if elevated intraocular pressure induced changes in the cellular environment can be identified.

Funded Activity Details

Start Date: 01-01-2012

End Date: 01-01-2014

Funding Scheme: Project Grants

Funding Amount: $471,979.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Medical and Health Sciences not elsewhere classified

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

blindness | glaucoma | ophthalmology | pathogenesis | vision loss

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