A novel role for E6AP in cellular senescence

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1026990

Funding Status
Closed

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Funded Activity Summary

Cancer is constantly being suppressed in our bodies by a process that stops damaged cells from growing: 'senescence'. The mechanism that translates the damage stimuli into this state of permanent cell arrest is only partially known. We have identified a protein that appears to drive this restraint. The possibility of manipulating this process to prevent and cure cancer makes it in important target to study.

Funded Activity Details

Start Date: 01-01-2012

End Date: 01-01-2014

Funding Scheme: Project Grants

Funding Amount: $512,282.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Cell Development, Proliferation and Death

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

DNA damage | RAS transformation | carcinogenesis | cell cycle regulation | human papillomavirus (HPV) | p53 | protein degradation | senescence | stress response | tumour suppression

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