Genetic programs orchestrated by AP-1 transcription factors in colorectal cancer progression

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1026228

Funding Status
Closed

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Funded Activity Summary

Colorectal cancer (CRC) is the third most common cancer worldwide. About half of all patients diagnosed with the disease die as a result of its spread in the body. This project will investigate the role that a specific DNA-binding protein plays in orchestrating gene expression programs required for CRCs to spread. The research will provide new insights into underlying mechanisms of CRC progression as well as identify new therapeutic targets for aggressive forms of the disease.

Funded Activity Details

Start Date: 01-01-2012

End Date: 01-01-2014

Funding Scheme: Project Grants

Funding Amount: $599,941.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Cancer Cell Biology

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

cancer progression | epithelial-mesenchymal transition (EMT) | gene expression | invasion | transcriptional regulation

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