Long-term effects of very low energy diet versus conventional diet on adiposity, lean body mass, muscle strength and bone density in obese adults, and mechanisms promoting changes

Funding Activity

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Funded Activity Summary

Very low energy diets (VLEDs) are increasingly used to treat obesity. Of concern is the fact that VLEDs induce adaptive responses that can inhibit loss of – and promote regain of – fatness (particularly belly fat) while decreasing lean body mass, muscle strength and bone density. This project will therefore determine whether VLEDs could have negative effects on body composition that increase the risk of metabolic disease, sarcopenia or osteoporosis, and if so, what are the mechanisms involved.

Funded Activity Details

Start Date: 01-01-2012

End Date: 01-01-2016

Funding Scheme: Project Grants

Funding Amount: $925,990.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Medical and Health Sciences not elsewhere classified

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

body composition | bone density | bone loss | central obesity | metabolic disease | muscle strength | muscle wasting | neuroendocrinology | obesity | weight loss