Transcriptional regulation of globin genes

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1025877

Funding Status
Closed

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Funded Activity Summary

Sickle cell anaemia and ?-thalassaemia are debilitating diseases for which there is no effective treatment. Patients require lifetime blood transfusions and drugs with significant side effects. These diseases are ameliorated in patients that express foetal haemoglobin into adulthood. The goal of this research is to understand how foetal haemoglobin is normally turned off at birth. This will ultimately help us discover how to switch it back on to treat patients.

Funded Activity Details

Start Date: 01-01-2012

End Date: 01-01-2015

Funding Scheme: Project Grants

Funding Amount: $658,467.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Biochemistry and Cell Biology not elsewhere classified

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

erythropoiesis | gene regulation | globin | haematopoiesis | sickle cell anaemia | thalassaemia | transcription factor | transcriptional regulation

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