Deciphering the hallmarks of transcriptional memory in human T lymphocytes

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1025718

Funding Status
Closed

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Funded Activity Summary

The immune system works by using powerful cellular weapons, such as memory T cells, to protect us from disease. Remarkably, memory T cells are not only able to remember their first encounter, but by learning are able to make genes respond faster upon re-exposure to the pathogen. This proposal aims to determine the molecular tags that mark genes in human memory T cells. Given the current global health challenges of devising effective vaccines, this will be critical for future disease therapy.

Funded Activity Details

Start Date: 01-01-2012

End Date: 01-01-2014

Funding Scheme: Project Grants

Funding Amount: $511,316.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Biochemistry and Cell Biology not elsewhere classified

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

T cells | chromatin structure | gene regulation | memory T-cells | transcriptional regulation

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