Functional Dissection of Invasion Motor Regulation in Toxoplasma gondii

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1025598

Funding Status
Closed

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Funded Activity Summary

The single-celled intracellular parasite Toxoplasma gondii is the cause of Toxoplasmosis and can be the basis of illness in immunocompromised individuals, eye disease and congenital birth defects. After host cell recognition Toxoplasma needs to activate the invasion machinery to establish a successful infection. We will reveal, at the molecular level, how Toxoplasma achieves this and then screen for drugs that inhibit this process. Compounds identified in this project could act as lead compounds to develop new treatments for Toxoplasmosis.

Funded Activity Details

Start Date: 01-01-2012

End Date: 01-01-2014

Funding Scheme: Project Grants

Funding Amount: $500,396.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Medical Parasitology

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

Toxoplasma gondii | infectious diseases | invasion | malaria | parasite | parasitic disease | phosphorylation | signalling pathways | toxoplasmosis

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