Mechanisms of propagation and containment of gene silencing

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1025549

Funding Status
Closed

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Funded Activity Summary

Long-term and heritable repression of genes by epigenetic mechanisms is essential for health but can also be dangerous if it goes wrong. Mathematical modelling and biochemical experiments will be used to understand how this gene silencing propagates and spreads along the DNA, and how it can be stopped from spreading too far.

Funded Activity Details

Start Date: 01-01-2012

End Date: 01-01-2015

Funding Scheme: Project Grants

Funding Amount: $272,223.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Biochemistry and Cell Biology not elsewhere classified

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

biochemistry | chromatin | epigenetics | gene silencing | mathematical modelling

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