Genes controlling the development of lung disease in normal and cystic fibrosis mice.

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/102523

Funding Status
Closed

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Funded Activity Summary

Patients with cystic fibrosis have a lethal predisposition to bacterial infection which causes irreversible lung disease. It is clear that even when patients carry the same mutation in the defective gene (CFTR), genetic background influences the course of the disease. Very little is known of the nature of these other genes and this proposal will identify those genes which influence the response of the CF lung to pathogens and in doing so may indicate novel therapeutic strategies.

Funded Activity Details

Start Date: 01-01-2001

End Date: 01-01-2002

Funding Scheme: NHMRC Project Grants

Funding Amount: $362,582.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Genetics Not Elsewhere Classified

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

Pseudomonas infection | cystic fibrosis | gene therapy | genetic mapping | host/pathogen interaction | molecular genetics | transgenic/knockout animals

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