Reduction of the cardiovascular response of psychological stress through blockade of orexin’s action on one of its receptors.

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/GNT1024891

Funding Status
Closed

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Funded Activity Summary

Anxiety, fear of challenges, frustration are part of modern life stressors. Our body reacts to these stressors by increasing blood pressure and heart rate, which in turn can harm our cardiovascular system and precipitate cardiovascular accidents. In this project we test a new class of drugs that act on a neurochemical system implicated in these particular responses. If our hypothesis is correct, one of these drugs could be used to relax the cardiovascular system and protect it in times of stress.

Funded Activity Details

Start Date: 01-01-2012

End Date: 01-01-2017

Funding Scheme: Project Grants

Funding Amount: $394,925.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Autonomic Nervous System

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

addiction | anxiety disorders | brainstem | cardiovascular physiology | cardiovascular risk factors | limbic system | neuropeptides | neuropharmacology | psychological stress | spinal cord

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