Exploring the role of microRNA and target processing variability in cardiac hypertrophy

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1024852

Funding Status
Closed

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Funded Activity Summary

microRNAs are gene regulators with critical roles in heart disease. How interactions between microRNAs and their messenger RNA targets change during disease is poorly understood. We hypothesise that these interactions are critically affected by altered processing of microRNAs and targets. We will thus characterise and validate such differences in healthy and diseased hearts. This will define gene regulatory changes underpinning heart disease and contribute to the search for better treatment.

Funded Activity Details

Start Date: 01-01-2012

End Date: 01-01-2014

Funding Scheme: Project Grants

Funding Amount: $605,190.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Systems Biology

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

RNA interference | RNA processing | cardiomyocytes | cardiovascular hypertrophy | disease mechanisms | gene expression | gene regulation | genomics | protein synthesis | splicing

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