Role of the drug metabolising enzyme arylamine N-acetyltransferase 1 in breast cancer

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1024769

Funding Status
Closed

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Funded Activity Summary

The current project will identify the molecular mechanism(s) that underpins the significant changes in phenotype seen in a range of human cancer cells. The expected outcomes will be to demonstrate that NAT1 is critical for the clearance of pABG in cancer cells. The results will be important in the context of understanding this family of intracellular enzymes and will change the current thinking on the function of the arylamine N-acetyltransferase in normal and cancer cells.

Funded Activity Details

Start Date: 01-01-2012

End Date: 01-01-2015

Funding Scheme: Project Grants

Funding Amount: $600,196.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Basic Pharmacology

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

acetylation | breast cancer | cell proliferation | drug metabolism | folate metabolism

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