Osteocalcin signalling modulates bone formation

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1024507

Funding Status
Closed

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Funded Activity Summary

Bone mass is regulated by a number of processes that originate in the brain, however, the mechanism whereby the bone signals to the brain is unknown. Osteoblasts, the cells that form bone, secrete a hormone, osteocalcin that signals in other tissues to control energy and glucose homeostasis. This proposal explores osteocalcin signalling in bone as well as in the brain as a potential feedback from bone to the brain.

Funded Activity Details

Start Date: 01-01-2012

End Date: 01-01-2014

Funding Scheme: Project Grants

Funding Amount: $592,333.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Biochemistry and Cell Biology not elsewhere classified

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

bone biology | hypothalamus | mouse models | neural pathways | osteoblast | osteocalcin | osteoporosis

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