Intraamniotic delivery of antiinflammatory drugs and antibiotics for the prevention of preterm birth

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1024467

Funding Status
Closed

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Funded Activity Summary

Inflammation arising from infection in the uterus is a common cause of premature (preterm) birth. Using a pregnant sheep model, plus human preterm membrane studies, we will explore the use of a combination of antibiotics and anti-inflammatory drugs given via intra-amniotic injection to prevent fetal and amniotic inflammation, while protecting mother and baby from unnecessary drug exposure. These studies will lead to the design of clinical trials aimed at preventing preterm birth.

Funded Activity Details

Start Date: 01-01-2012

End Date: 01-01-2015

Funding Scheme: Project Grants

Funding Amount: $568,281.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Obstetrics and Gynaecology

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

antibiotic therapy | fetal membranes | inflammation | inhibitors | obstetrics | parturition | perinatal | pharmacokinetics

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