Is low dose amitriptyline more effective than placebo in the management of chronic, neuropathic low back pain? A double-blind, randomized, placebo-controlled trial with an economic evaluation

Funding Activity

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Funded Activity Summary

Chronic low back pain is a major public health problem in Australia. Antidepressants are a common treatment for low back pain, with physicians often prescribing them at low doses for the treatment of pain. However, the use of antidepressants for low back pain is unproven. We aim to perform a clinical trial to examine whether antidepressants are more effective than placebo in reducing pain and disability in patients with chronic low back pain.

Funded Activity Details

Start Date: 01-01-2012

End Date: 01-01-2014

Funding Scheme: Project Grants

Funding Amount: $306,889.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Clinical Sciences not elsewhere classified

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

antidepressants | economic evaluation | low back pain | pain | randomised controlled trial (RCT)