Phosphoinositide 3-kinase signalling and skeletal muscle mass.

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1024308

Funding Status
Closed

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Funded Activity Summary

Maintenance of skeletal muscle mass is essential for human health and locomotion. In ageing and cancer, loss of muscle mass leads to severe weakness and immobilization causing morbidity and mortality. This grant aims to characterise a novel gene that when deleted in mice leads to significant muscle damage. The molecular pathways within the cell that lead to the observed muscle damage will be investigated and this may provide insights into the pathways that control muscle damage and its regeneration

Funded Activity Details

Start Date: 01-01-2012

End Date: 01-01-2014

Funding Scheme: Project Grants

Funding Amount: $597,598.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Signal Transduction

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

cardiac hypertrophy | integrins | intracellular signal transduction | skeletal muscle hypertrophy | skeletal muscle wasting

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