The plasmalemmal calcium pump and vascular smooth muscle cell proliferation.

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/102426

Funding Status
Closed

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Funded Activity Summary

Excessive growth of smooth muscle cells can lead to adverse effects in our arteries. The level of calcium inside the muscle cells that line our arteries appears to regulate their growth. In these studies we will assess the changes in the synthesis (expression) of a pump which removes calcium from cells. We will also characterise the effects of modifiers of cell growth on the expression of the calcium pump. The effect of directly inhibiting the production of the calcium pump, on the growth of smooth muscle cells and the regulation of calcium will be determined for the first time.

Funded Activity Details

Start Date: 01-01-2000

End Date: 01-01-2002

Funding Scheme: NHMRC Project Grants

Funding Amount: $179,593.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Medical biotechnology diagnostics (incl. biosensors)

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

calcium | calcium pump | cardiovascular disease | cellular signalling | pharmacology | signal transduction | smooth muscle proliferation | vascular smooth muscle

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