Investigation of steroidogenesis as a mechanism of castration resistance in human prostate cancer

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1024081

Funding Status
Closed

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Funded Activity Summary

Prostate cancer is critically dependent upon continued testosterone stimulation, even when the disease becomes resistant to existing hormonal therapies that suppress serum levels. The source of this testosterone is currently unclear. This study aims to identify the site of testosterone synthesis in patients with prostate cancer, and determine the relevance of continued testosterone signalling in patients treated with 'super castrating' hormonal therapy.

Funded Activity Details

Start Date: 01-01-2012

End Date: 01-01-2015

Funding Scheme: Project Grants

Funding Amount: $419,076.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Nephrology and Urology

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

androgen | androgen independent prostate cancer | cancer cell biology | prostate cancer | steroidogenesis

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