An investigation into pathogen-specific factors required for drug-resistance and viability of Candida albicans

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1023973

Funding Status
Closed

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Funded Activity Summary

We identified proteins required for growth and drug resistance of the fungus Candida albicans, a major hospital-acquired human pathogen. Candida infections target the immunocompromised and mortality is huge (?30-50%). We will use cell biology, genetics and biochemistry to characterise these proteins. Importantly, these factors are present in fungi, but absent from humans. Therefore our study will help development of new strategies for antifungal treatments.

Funded Activity Details

Start Date: 01-01-2012

End Date: 01-01-2014

Funding Scheme: Project Grants

Funding Amount: $337,614.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Cellular Interactions (incl. Adhesion, Matrix, Cell Wall)

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

Candida albicans | biochemistry | fungal pathogenesis | mitochondria | molecular genetics

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