Innate immune responses to rotavirus infection

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1023786

Funding Status
Closed

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Funded Activity Summary

Rotavirus is the main cause of severe diarrhoea in children worldwide. In this project, we aim to understand the nature of the first-line immune response to rotavirus in the gut, and elucidate how RV counteracts this response to promote infection. These studies will increase our understanding of how rotavirus causes disease, and facilitate the choice of rotavirus targets for drug development and improved vaccines.

Funded Activity Details

Start Date: 01-01-2012

End Date: 01-01-2014

Funding Scheme: Project Grants

Funding Amount: $534,200.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Medical Virology

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

JAK/STAT pathway | immune evasion | innate immunity | interferon (IFN) | nuclear factor kappa-B (NF-KB) | nuclear import | rotavirus infection | transcriptional regulation

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