Research Fellowship

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1022870

Funding Status
Closed

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Funded Activity Summary

Cancer is linked to mutations in a large variety of genes but how these changes impact on cell behaviour is often unknown. We are using functional genomics in zebrafish to identify genes that are essential for rapid rates of proliferation by intestinal epithelial cells. Seven genes have been cloned so far and our next task is to analyse, using mouse models and human cancer transcriptome analysis, whether any are indispensable for cancer growth and thereby present suitable targets for therapy.

Funded Activity Details

Start Date: 01-01-2012

End Date: 01-01-2016

Funding Scheme: Research Fellowships

Funding Amount: $611,574.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Developmental Genetics (incl. Sex Determination)

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

colon cancer mechanisms | developmental genetics | drug delivery systems | functional genomics | gene discovery | gene expression | intestinal mucosa | mouse models | positional cloning | zebrafish

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