Novel GPCR transactivation of serine kinases in vascular disease

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1022800

Funding Status
Closed

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Funded Activity Summary

All of biology and disease is based on cells receiving signals from hormones and growth factors via cell surface receptors. Cells integrate these signals to give a response which may be cell growth or the secretion of further hormones and growth factors. Signals from receptors can intersect to modify the response. This project will explore a new interaction we have discovered where a hormone activates its receptor to cause the activation of a growth factor receptor potentially providing new drug targets in cardiovascular disease.

Funded Activity Details

Start Date: 01-01-2012

End Date: 01-01-2015

Funding Scheme: Project Grants

Funding Amount: $386,565.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Cardiology (incl. Cardiovascular Diseases)

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

atherosclerosis | diabetic vascular complications | extracellular matrix | growth factor | signalling pathways

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