Mechanisms of PTEN regulation by Ndfip1 and their biological consequences for neuron survival during brain injury

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1022728

Funding Status
Closed

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Funded Activity Summary

We have discovered a new protein (Ndfip1) that protects brain cells from death after brain injury from trauma and stroke. We will investigate why this protein is activated only in some, but not in other, brain cells after injury. In this application, we will study the mechanisms behind neuron protection, and use this information to explore how to increase the number of brain cells activating Ndfip1.

Funded Activity Details

Start Date: 01-01-2012

End Date: 01-01-2014

Funding Scheme: Project Grants

Funding Amount: $686,640.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Cellular Nervous System

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

brain cell cultures | brain cell damage | brain development | brain ischaemia | molecular neuroscience

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