Identification of novel targets for treatment of heart failure

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1022678

Funding Status
Closed

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Funded Activity Summary

Hearts respond to stimulation by activation of cell surface receptors. We have found that two very closely related receptors have opposing effects on the heart; one is beneficial and the other promotes disease. The planned studies will investigate exactly what explains this difference. This will identify critical factors that protect or damage the heart and is expected to provide suitable targets for drug development.

Funded Activity Details

Start Date: 01-01-2012

End Date: 01-01-2015

Funding Scheme: Project Grants

Funding Amount: $486,873.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Basic Pharmacology

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

adrenoceptors | contractility | hypertrophy | phospholipase C | signalling pathways | transgenic mouse

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