Knowledge, Identification and Exploitation of dopaminergic axon guidance cues will improve cell replacement therapy for ParkinsonÍs disease.

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1022637

Funding Status
Closed

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Funded Activity Summary

Many obstacles exist for cell transplantation in ParkinsonÍs Disease; namely poor graft survival, restoration of appropriate circuitry and adequate nerve fiber growth from new cells. Using knowledge of how neural circuits are established during fetal development, we will attempt to recapitulate these events following transplantation. Further, we will identify new and novel cues in regulating the connectivity and growth of these nerve fibers.

Funded Activity Details

Start Date: 01-01-2012

End Date: 01-01-2014

Funding Scheme: Project Grants

Funding Amount: $481,797.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Central Nervous System

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

Parkinson disease | axon guidance | axon regeneration | neural development | neural transplantation

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