Cellular therapy for genetic liver disease exploiting induced pluripotent stem cells and liver progenitor cells

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1022498

Funding Status
Closed

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Funded Activity Summary

It has recently become possible to genetically reprogram mature cell types in the body to become stem cells and then redirect them to become any other cell type desired. This technology has immense, but as yet unrealised, diagnostic and therapeutic potential. In this project we seek to develop cellular therapies for metabolic liver disease. Specifically, we plan to generate liver cells from skin cells and to test the therapeutic effectiveness of these cells by curing liver disease in mice.

Funded Activity Details

Start Date: 01-01-2012

End Date: 01-01-2014

Funding Scheme: Project Grants

Funding Amount: $797,185.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Biochemistry and Cell Biology not elsewhere classified

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

cell biology | differentiation | liver disease | pluripotential | regenerative medicine | stem cell therapy

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