Role of ABCA8 transporter in oligodendroglial lipid regulation and multiple system atrophy

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1022325

Funding Status
Closed

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Funded Activity Summary

Multiple system atrophy (MSA) is a rapid-onset brain disorder impacting on multiple functions of the body resulting in death. The cause of MSA is unknown and there is no cure. In MSA brains, the oligodendroglial cells are impaired and cannot properly make myelin (specialized lipid membrane), which is required for the proper functioning of the nerve cells in the brain. The aim of this project is to find out how changes in lipid in the brain impact on the MSA disease process.

Funded Activity Details

Start Date: 01-01-2012

End Date: 01-01-2014

Funding Scheme: Project Grants

Funding Amount: $651,516.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Cellular Nervous System

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

gene regulation | lipid disorders | lipid metabolism | molecular basis of disease | molecular neuroscience | multiple system atrophy | myelin | protein function | transporters

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