Urokinase is a key mediator of airway inflammation and tissue remodelling in asthma

Funding Activity

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Funded Activity Summary

The scarring of airway tissue in asthma increases the difficulty of breathing. There is no effective treatment for airway scarring in severe asthma. This study looks at how proteins involved in dissolving blood clots influence wound healing and scarring in the airways. A better understanding of airway tissue scarring will lead to possible treatments for more serious forms of asthma which remain a major health and economic burden to our community.

Funded Activity Details

Start Date: 01-01-2012

End Date: 01-01-2015

Funding Scheme: Project Grants

Funding Amount: $556,425.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Medical and Health Sciences not elsewhere classified

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

airway inflammation | airway remodelling | airway smooth muscle | asthma | asthma therapy | drug targeting | pharmacological intervention | plasminogen | urokinase