Pharmacology of Potential Anti-Tumour Agents: Iron and Copper Chelators of the ApT, BpT and DpT Classes

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1021607

Funding Status
Closed

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Funded Activity Summary

Cancer cells take up more of the essential nutrients copper and iron than normal cells. Increased metabolism of these metals is linked to tumour growth progression. Our laboratory has developed compounds that bind these metals in tumours. Our studies suggest our novel compounds display a novel tumour targeting strategy which may explain their ability to also overcome drug resistance. This unique mechanism of action is crucial to understand for the development of novel anti-cancer agents.

Funded Activity Details

Start Date: 01-01-2012

End Date: 01-01-2015

Funding Scheme: Project Grants

Funding Amount: $647,137.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Pharmacology and Pharmaceutical Sciences not elsewhere classified

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

drug development | medicinal chemistry | molecular pharmacology | pharmaceutics | pharmacology

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