Defining the stage specific requirements for Bcl-2 family members in the development and maintenance of B cell memory

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1021374

Funding Status
Closed

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Funded Activity Summary

Both vaccinations and pathogenic infections provoke an immune response. Our immune system ñmemorizesî this response, enabling a faster and stronger reaction upon re-encounter. This memory requires specialized cells of the immune system, some of which secrete antibodies and some of which patrol the body. Remarkably, these cells can live for decades in humans and provide immunity. In this project we will study the roles of specific proteins regulating the generation and survival of memory cells.

Funded Activity Details

Start Date: 01-01-2012

End Date: 01-01-2014

Funding Scheme: Project Grants

Funding Amount: $632,438.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Humoural Immunology and Immunochemistry

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

B cells | BAX | Bcl-2 | affinity maturation | antibody | apoptosis | immunologic memory

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