Dissecting associations of estradiol and testosterone with cardiovascular outcomes.

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1021326

Funding Status
Closed

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Funded Activity Summary

Controversy persists over whether falling testosterone (T) levels in ageing men increase risk of cardiovascular disease (CVD). T is converted by the enzyme aromatase into estradiol (E2). We will assess whether men with abnormal E2 levels are at risk of CVD, more so than men with low T. We will assess whether differences in the aromatase gene which alter E2 levels also influence the risk of CVD. The results will clarify the importance of hormones to CVD and guide new approaches to its treatment.

Funded Activity Details

Start Date: 01-01-2012

End Date: 01-01-2014

Funding Scheme: Project Grants

Funding Amount: $435,082.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Geriatrics and Gerontology

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

ageing | aromatase | cardiovascular disease | estradiol | testosterone

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