Reprogramming of Ataxia Telangiectasia fibroblasts to generate iPS cells

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1021005

Funding Status
Closed

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Funded Activity Summary

Ataxia telangiectasia (A-T) is a human genetic disorder characterised by immunodeficiency, cancer predisposition and neurodegeneration. The aim of this project is to generate adult stem cells from A-T patient as a model system to investigate the nature of the nervous system defect in this disorder. These adult stem cells will be employed to produce neuronal cells which will be a resource for screening for therapeutic compounds to treat A-T patients.

Funded Activity Details

Start Date: 01-01-2012

End Date: 01-01-2015

Funding Scheme: Project Grants

Funding Amount: $601,386.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Neurogenetics

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

DNA damage | ataxia telangiectasia | cell biology | genetics | neuroscience | signal transduction | stem cells

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