Does inhibition of myeloperoxidase attenuate atherosclerosis?

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1020776

Funding Status
Closed

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Funded Activity Summary

This project examines whether inhibition of a protein that produces bleach and is part of the immune system inhibits the stiffening of arteries, i.e. the major cause of cardiovascular disease that leads to heart attack and stroke. The project uses a pharmacological approach, employing a new class of chemical compounds. If successful, the project will contribute to the establishing of a novel therapeutic target to combat cardiovascular disease.

Funded Activity Details

Start Date: 01-01-2012

End Date: 01-01-2015

Funding Scheme: Project Grants

Funding Amount: $572,659.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Cardiology (incl. Cardiovascular Diseases)

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

antioxidant | atherosclerosis | cardiovascular disease | cardiovascular pharmacology | drug development | endothelial dysfunction | endothelium-dependent relaxation | lipoproteins | oxidative stress | protein oxidation

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