Wbp2, a new regulator of the Hippo tumor suppressor pathway

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1020318

Funding Status
Closed

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Funded Activity Summary

The Hippo pathway is a key regulator of tissue growth. It was first discovered in vinegar flies and plays a similar role in mammals. We aim to define the mechanism by which a newly-identified Hippo pathway protein, Wbp2, functions to control growth. These studies will be performed in flies and confirmed in mammalian cells. Ultimately, our studies will shed light on how tissue growth is controlled, and have the potential to inform the way that we treat human cancers and tissue growth disorders.

Funded Activity Details

Start Date: 01-01-2012

End Date: 01-01-2014

Funding Scheme: Project Grants

Funding Amount: $585,860.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Cell Development, Proliferation and Death

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

Drosophila | cancer cell biology | organ growth and development | signalling | transformation

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