Roles of the hepatitis C virus glycoprotein E2 variable regions in virus entry, immunogenicity and immune evasion.

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1020175

Funding Status
Closed

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Funded Activity Summary

Hepatitis C Virus infects 200 million people world-wide with over 200,000 Australians infected with the disease. This project will examine how the surface proteins of HCV change their shape to evade antibody responses and how this effects the outcome of infection. We will further characterize a vaccine that elicits protective immunity to HCV to identify the optimal formulation for clinical trials.

Funded Activity Details

Start Date: 01-01-2012

End Date: 01-01-2014

Funding Scheme: Project Grants

Funding Amount: $682,820.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Medical Virology

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

antibody | chronic infection | glycoproteins | hepatitis C virus | receptor binding | structure-function | vaccine design | vaccine development

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