The Characterisation of the Mechanism of Beta Amyloid Toxicity in Alzheimer's Disease

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1018107

Funding Status
Closed

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Funded Activity Summary

Alzheimer�s disease (AD) is the most common form of dementia and is characterised by the beta amyloid peptide (A_) found in plaques in the brain. A structural transition to aggregated/ oligomeric forms of A_ is accompanied by a gain of toxicity. In this study the biological and biophysical characterisation of a variety of A_ peptides will be performed. The study will also use oligomers from cell culture media and brain tissue that have been influential in AD research but poorly characterised.

Funded Activity Details

Start Date: 01-01-2011

End Date: 01-01-2014

Funding Scheme: NHMRC Postgraduate Scholarships

Funding Amount: $94,430.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Neurology and Neuromuscular Diseases

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

Alzheimer disease | ageing population | amyloid beta-protein | cell biology | molecular biology | neurodegeneration

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